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CURRENT LEARNING IN PALLIATIVE CARE

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Helping patients with symptoms other than pain 1: Constipation

Introductory Level

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FURTHER READING

Papers

Agra Y. Sacristan A. Gonzalez M. Ferrari M. Portugues A. Calvo MJ. Efficacy of senna versus lactulose in terminal cancer patients treated with opioids. Journal of Pain & Symptom Management. 1998: 15(1):1-7.

Bruera E. Suarez-Almanzor M. Velasco A. Bertolino M. MacDonald SM. Hanson J. The assessment of constipation in terminal cancer patients admitted to a palliative care unit: a retrospective review. Journal of Pain & Symptom Management, 1994: 9(8):515-9.

Cleveland MV. Flavin DP. Ruben RA. Epstein RM. Clark GE. New polyethylene glycol laxative for treatment of constipation in adults: a randomized, double-blind, placebo-controlled study. Southern Medical Journal. 2001: 94(5): 478-81.

Fallon MT. Hanks GW. Morphine, constipation and performance status in advanced cancer patients. Palliative Medicine. 1999: 13(2):159-60.

Fallon M, O’neill B. ABC of palliative care: constipation and diarrhoea. British Medical Journal, 1997; 315: 1293-6.

Mancini I. Bruera E. Constipation in advanced cancer patients. Supportive Care in Cancer. 1998; 6(4):356-64.

Nugent M. Davis C. Brooks D. Ahmedzai SH. Long-term observations of patients receiving transdermal fentanyl after a randomized trial. Journal of Pain & Symptom Management. 2001: 21(5):385-91.

O'Mahony S. Coyle N. Payne R. Current management of opioid-related side effects. Oncology (Huntington). 2001; 15(1): 61-73. 77.

Prather CM. Ortiz-Camacho CP. Evaluation and treatment of constipation and fecal impaction in adults. Mayo Clinic Proceedings. 1998; 73(9): 881-6.

Sykes NP. A volunteer model for the comparison of laxatives in opioid-related constipation. Journal of Pain & Symptom Management. 1996: 11(6):363-9.

Sykes NP. The relationship between opioid use and laxative use in terminally ill cancer patients. Palliative Medicine. 1998: Thorpe DM. Management of opioid-induced constipation. Current Pain & Headache Reports. 2001: 5(3):237-40.

Wiesel PH, Norton C, Brazzelli M. Management of faecal incontinence and constipation in adults with central neurological diseases The Cochrane Database of Systematic Reviews, 2002; 2.

Xing JH. Soffer Diseases of the Colon & Rectum. 2001: 44(8):1201-9.

Resource books and websites

A Guide to Symptom Relief in Palliative Care, 5th ed. Regnard C, Hockley J.  Abingdon: Radcliffe Medical Press, 2004

Oxford Textbook of Palliative Medicine  3rd ed. Doyle D, Hanks G, Cherny NI, Calman K eds. Oxford : Oxford University Press, 2003.

PCF2- Palliative Care Formulary, 2nd ed. Twycross RG, Wilcock A, Charlesworth S. Abingdon: Radcliffe Medical Press, 2003.  Also on www.palliativedrugs.com

Symptom Management in Advanced Cancer, 3rd edition. 2001.   Twycross RG, Wilcock A.   Abingdon: Radcliffe Medical Press.